This paper presents the initial reflections in the frame of Subtask 1 – Setting the Metrics of the IEA EBC Annex 68 – Indoor Air Quality Design and Control in Low Energy Residential Buildings. The first step of IEA Annex 68 aims at summarizing the current knowledge on target pollutants for residential buildings and at evaluating indoor air quality (IAQ), i.e. how to define indices that provide useful information allowing to achieve low risks for health in indoor spaces, and how to enable the comparison of solutions for achieving high IAQ taking into account energy efficiency. At this stage of the project, there is no single definition of the metric that would allow meeting these objectives. However, the potential elements of such definition presented in this paper regarding both IAQ and energy indices will be further investigated in the course of the project.