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The software DOMUS has been developed to model coupled heat and moisture transfer in multi-zone buildings. DOMUS has been conceived to be a very user-friendly software so that to stimulating a larger number of users in Brazil to use building simulation software and meet national energy conservation program goals. Besides this aspect, as the weather in Brazil permits the analysis of building architecture, thermal comfort passive strategies can be easily analyzed. DOMUS models predict temperature profiles within multi-layer walls for any time step and the temperature and relative humidity for each zone. In the article, we will show the DOMUS 1.0 models and interface and some capabilities.